The Impact of Azathioprine-Associated Lymphopenia on the Onset of Opportunistic Infections in Patients with Inflammatory Bowel Disease. Eur J Gastroenterol Hepatol. Feb;23(2) doi: /MEG. 0bea2. Natural history of azathioprine-associated lymphopenia in. receive thiopurines (azathioprine (AZA), . Figure 1 Azathioprine metabolism. .. azathioprine-associated lymphopenia on the onset of.
Azathioprine for management of auto-immune conditions . Please note that lymphopenia should be expected (lymphocyte count < x/l suggests. Although drug-induced lymphopenia is a common finding, its consequences are poorly understood. Key words:Lymphopenia; Leukopenia; Immunosuppression; Mercaptopurine metabolites; Inflammatory Bowel Disease; Azathioprine; 6-mercaptopurine.
Could Imuran cause Lymphopenia? We studied Imuran users who have side effects from FDA and eHealthme. Among them, 19 have Lymphopenia. Physicians should inform patients of the risk of malignancy with IMURAN. See . In a detailed case report,13 documented lymphopenia, diminished IgG and IgM. On consultation with the hematology department, azathioprine therapy was discontinued; however, severe peripheral lymphopenia persisted (Fig. 1). Known adverse effects of azathioprine include gastrointestinal symptoms, nausea, fatigue and malaise, along with myelosuppression, lymphopenia, neutropenia.